Introduction
Deworming pregnant dogs is essential to protect the dam and her puppies from congenital parasite transmission, particularly roundworms and hookworms. However, medication safety and timing are critical to avoid adverse effects on developing fetuses. This article presents veterinarian-approved tips for safely deworming pregnant dogs.

1. Understanding Transmission Risks

• Transplacental Transfer: Roundworm larvae can migrate to the uterus and infect puppies in utero.

• Transmammary Transfer: Larvae excreted in the mother’s milk can infect nursing puppies.

• Health Implications: Infected puppies risk malnutrition, poor growth, and severe gastrointestinal distress.

2. Recommended Deworming Protocols

A. Fenbendazole (Panacur®)

• Dosage: 50 mg/kg orally once daily from Day 40 of gestation through Day 14 postpartum.

• Safety Profile: Extensive studies show no teratogenic effects in dogs at this dosage.

• Administration Tips: Divide dose with meals to minimize gastrointestinal upset.

B. Pyrantel Pamoate

• Dosage: 5 mg/kg orally at Day 40 of gestation, repeated weekly until whelping.

• Use Case: Targets roundworms and hookworms; considered safe in late gestation.

• Combination Therapy: Often combined with fenbendazole postpartum for broader coverage.

C. Selamectin (Revolution®)

• Dosage: Topical application at 6 mg/kg once during pregnancy (around Day 40).

• Advantages: Provides protection against fleas and certain intestinal parasites.

• Considerations: Avoid use in dogs under 6 weeks of age—safe for pregnant dams with veterinarian approval.

3. Timing and Scheduling

• Day 40 of Gestation:

  • Initiate fenbendazole and pyrantel pamoate to reduce in utero transmission.

• Weekly Pyrantel Doses:

  • Continue pyrantel until parturition to minimize worm burden in milk.

• Postpartum Continuation:

  • Extend fenbendazole to 2 weeks after whelping to protect nursing puppies.

4. Monitoring and Veterinary Oversight

• Fecal Exams:

  • Conduct a baseline fecal test before Day 40.

  • Repeat testing 2 weeks postpartum to confirm parasite clearance.

• Blood Work:

  • Evaluate dam’s complete blood count and chemistry profiles prior to medication.

  • Monitor for anemia or hepatic strain throughout pregnancy.

• Ultrasound and Physical Exams:

  • Track fetal development; ensure dam remains healthy and stress-free.

5. Nutrition and Supportive Care

• Balanced Diet:

  • Provide high-quality, nutrient-dense food to support increased energy demands and immune function.

  • Supplement with omega-3 fatty acids to reduce inflammation.

• Hydration:

  • Ensure fresh water is always available; deworming can cause mild dehydration.

  • Monitor intake daily.

• Environmental Management:

  • Keep whelping area clean; sanitize bedding weekly to prevent reinfection.

  • Limit exposure to contaminated soil or other animals carrying parasites.

Conclusion
Safe deworming of pregnant dogs involves a precise regimen—fenbendazole from Day 40 through two weeks postpartum, supplemented by weekly pyrantel pamoate. Close veterinary supervision, regular fecal testing, and supportive nutrition ensure the dam and her litter remain healthy and parasite-free.